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What is Champix?

Champix is the brand name for Varenicline, a drug that helps smokers stop smoking. By mimicking the physical effects of nicotine, it reduces the urge to smoke while alleviating the horrible symptoms of withdrawal. Read on to learn more about this popular drug. Buy Champix UK and know more about it. This medication is often used in conjunction with counseling support and behavior modification to help people quit smoking.

When is Champix used?

Take Champix (tablets) daily for seven days before the day you have set as the day you quit smoking. The main goal here is to get your body used to the medication before you quit smoking and switch to tablets only. Please note that having the willingness to quit is vital so Champix can help you. In this way, you can reduce physical dependence on tobacco and switch to a harmless alternative that will later be abandoned too. If you do not have a quit date before you start taking Champix, you can start taking it and then choose a date eight to 35 days later.

How is Champix used?

Buy Champix Online and Take this tablet twice a day with water. Take it after eating (after breakfast and dinner). Once you have reached your quit date, keep taking it for 11 weeks. Please note that Champix is a prescription medicine and cannot be purchased from a pharmacy. Most people consider this treatment sufficient to stop smoking. However, some people need additional treatment. If this is the case, talk to your doctor, who will review your situation.

Dose

The usual dose is one 0.5 mg tablet per day for the first three days. The dose is repeated twice a day for the next four days (first week). At this point, after you have reached your quit date, you start taking 1 mg twice a day for 11 weeks. Therefore, the full treatment is usually 12 weeks.

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Champix smoking pills

Lack of understanding of the essence of nicotine addiction and numerous attempts to quit smoking lead to the fact that people begin to believe anyone, especially when it comes to doctors. People in white coats offer a lot of options to help smokers: casts and gum, lozenges and inhalers, needles, etc.

In January 2018, Tel Aviv University published a study on the effectiveness of nicotine replacement therapy. Among the 28,000 participants in the study, only 20% did not smoke after a year after undergoing therapy. However, due to the fact that this technique is officially recognized by the WHO, new drugs are constantly appearing, the manufacturers of which claim that this tool will definitely help to quit smoking. And today we want to talk about one of them: the medicine "Champix" or Champix (in the United States: "Chantix").

Champix is a common smoking cure

The active substance in Champix is varenicline. It was first synthesized in 2006 in the United States under the leadership of Jotem Coe, who specializes in the treatment of depression, schizophrenia, and addiction. The basis of the development was a modified cytisine molecule (part of Cyperkuten, Tabex, Cytitone).

Varenicline's job is to bind to and stimulate neuronal nicotinic acetylcholine receptors. This stimulation is similar to nicotine but to a lesser extent. Varenicline has a greater relationship with these receptors than nicotine, so it blocks their action. In other words, the smoker no longer receives the usual "pleasure" from cigarettes. In the WHO recommendations for the treatment of tobacco dependence, varenicline is assigned to the first group of drugs, which is recommended to use first of all with the pharmacological method of treatment of addiction to nicotine.

App Features

Buy Champix, as well as other similar drugs, it is necessary according to a certain scheme. The manufacturer claims that the best effect of varenicline in the body is achieved in this way. The main feature of taking this drug can be called that before taking the person should choose the estimated date to quit smoking and start taking 1-2 weeks before this date. The total duration of taking Champix is 12 weeks. However, this duration of varenicline is not always sufficient, therefore, the administration can be continued for another 12 weeks.

The manufacturer recommends gradually increasing the dose of the drug. The first 3 days you should take a total of 500 mcg once a day. For the next 4 days, varenicline is taken in the same dose, but already 2 times a day. From day 8 to the end of treatment, the dose increases; now it should be 1 μg 2 times a day. At the same dose, Champix should be taken during the second 12 weeks to consolidate the effect of smoking cessation.

The main side effect that occurs in 25% of cases is nausea. In second place are insomnia and strange dreams at the same time: 12%. Also, while taking varenicline, keep in mind:

  • decreased mood, irritability;
  • the appearance of feelings of anger and anxiety;
  • The altered concentration of attention;
  • increased appetite and, as a consequence, an increase in body weight.

All of these effects occur in most cases in the initial stage of taking Champix. This can be explained by the body's "addiction" to varenicline. This is in part why the dosage regimen prescribes a gradual increase in dosage.

According to the description of the company, the effectiveness of Champix is about 30% (only in combination with a visit to a psychologist).

Two reasons not to take Champix tablets

First reason

Every day we see the emergence of "new effective drugs", and people are in a rush to buy and try them quickly. At the same time, they are not worried about the possible side effects, complications, and consequences of taking them. They do not even try to find out at an elementary level what they are offered to buy and what exactly the manufacturers of such products promise.

Painkillers can be an illustration of this situation (for example, Tramadol, which, as stated above, is not addictive, but even today, narcologists are still shocked by the consequences that this drug caused in people).

As for antidepressants, the complications of taking Valium and Lidium are already known. And the coaxial drug horrified not only narcologists but the whole world. List this list indefinitely.

If you have an education in the field of medicine, then you have an idea about the cholinergic and other systems, their relationship, as well as the effect that occurs when exposed to a particular receptor. And that makes it terrifying. And not just for smokers who use these drugs to stop smoking.

In principle, people should be wary of drugs that are placed as smoking pills and that have a number of side effects. Unfortunately, in Russian, there is little information about such drugs. There is only the data provided by the manufacturers and sellers of these funds.

But even from the instructions for Champix, you can know the side effects of these pills from smoking. In addition to nausea, diarrhea, and "harmless" dizziness, smokers who take this remedy may also experience manifestations such as strange dreams, depression, and suicidal moods. Also in December 2017, Canadian researchers published in the American Journal of Respiratory and Critical Care Medicine a study on the relationship of varenicline with a 34% increase in the frequency of hospitalizations and doctor visits for symptoms associated with cardiovascular disease.

Another study, EAGLES (an assessment of adverse events in the global smoking cessation study), conducted in 16 countries and 140 centers with more than 8,000 participants, showed the special effect of Champix on a person's mental state. Then, the possibility of severe neuropsychiatric symptoms was revealed in patients who were trying to quit smoking with the help of this drug. This is especially true for people who already have mental disorders in the history of the disease, for example, depression, post-traumatic conditions, anxiety, bipolar disorder, etc.

Few have heard of the US Food and Drug Administration. It can be said that the US Department of Health, abbreviated FDA. Its main task is to control the quality of food and pharmaceutical products. And today, disputes constantly arise between the world's largest pharmaceutical company, Pfizer, and the specialists of this organization. Therefore, the FDA constantly requires that Pfizer indicates in its instructions to Champix all its possible contraindications, side effects, and consequences, which greatly prevents the promotion of this drug on the market.

Champix Smoking Cessation is currently sold throughout the world, including the United States. The BBC channel conducted its investigation and tried to find out if this is really the case.

The second reason

Like any drug addiction, smoking has two aspects, one of which is psychological dependence. It is she who forces people to reach for a cigarette again. Just think:

  • Why do women start smoking again after 9 months of cigarette abstinence and having a baby?
  • Why are there people who might not touch cigarettes for weeks?

Just for the reason that this dependence is not physical, but psychological.

If the problem consisted only of the interaction of nicotine with acetylcholine receptors, then all nicotine replacement drugs would work perfectly: gum, patches, drugs like Tabex. However, reviews show that the success rate of Tabex or patches and other smoking drugs is only 5-14% per year.

It is curious that the Pfizer company (manufacturer of Champix), when describing the clinical studies of its medicine, indicates the importance of the psychological attitude of the person who stops smoking. The document, available by reference, states that smoking cessation therapy will be most effective if a person is motivated to quit an addiction. To this end, you are advised to provide appropriate materials and provide psychological support. The Ministry of Health of the Russian Federation also notes the need to combine drug therapy with psychological work on motivation to get rid of addiction.

But let's go back to the Pfizer study. There, in paragraph 14, a description of Champix clinical trials is provided, which demonstrates its effectiveness. And here it is important that all dropouts during the study receive weekly consultations. That is, in fact, they worked on their psychological dependence. The success of the drug may not be due at all to its chemical effect, but to the fact that people simply decided to quit smoking. Furthermore, the fact that the study was carried out by the manufacturing company itself, which is interested in its success, cannot be ignored.

So how do you quit smoking?

We confidently declare that it is very easy! Fortunately, although nicotine is a drug, it is very light. And weaning occurs almost imperceptibly. But only on the condition that you do not want to smoke, that no pill can eliminate. Only in this case, you will not face depression and emotional stress, it will not be necessary to take antidepressants or other drugs.

Take care of yourself and stay healthy! And yes, Stop smoking with Champix.